Epic

There are currently 113 playable Epic characters in the game.

Abigail Brand (Commander of S.W.O.R.D.)	Adam Warlock (Infinity Watch)	Agatha Harkness (Coven Leader)	Apocalypse (Classic)
Arcade (Edward Acra)	Archangel (Classic)	Aunt May (Golden Oldie)	Baron Zemo (Helmut Zemo)
Beta Ray Bill (Korbinite Cyborg)	Big Wheel (Jackson Weele)	Black Bolt (Inhuman King)	Black Panther (Civil War)
Black Widow (Natasha Romanoff)	Cable (Nathan Summers)	Captain America (First Avenger)	Captain America (Infinity War)
Captain Marvel (Galactic Warrior)	Carnage (Prophet of Knull)	Chasm (Ben Reilly)	Colossus (Phoenix Five)
Crystal (Crystalia Amaquelin)	Cyclops (Phoenix Five)	Daredevil (Matt Murdock)	Deadpool (Hotpool)
Deadpool (Spirit of Vengeance)	Doctor Doom (God Emperor)	Doctor Octopus (Classic)	Doctor Strange (Sorcerer Supreme)
Electro (Francine Frye)	Elektra (Woman Without Fear)	Elsa Bloodstone (Space Hunter)	Emma Frost (Phoenix Five)
Gambit (Classic)	Gamora (Deadliest Woman)	Gargantos (Multiverse of Madness)	Ghost Rider (Robbie Reyes)
Goose (Flerken Family)	Gorgon (X of Swords)	Green Goblin (Norman Osborn)	Havok (Classic)
Hawkeye (Clint Barton)	Heimdall (The Gatekeeper)	Hela (Goddess of Death)	High Evolutionary (Awesome Mix Vol. 3)
Hit-Monkey (E.D.I. Suit)	Hobgoblin (Roderick Kingsley)	Howard the Duck (Juggerduck)	Iceman (Bobby Drake)
Iron Man (Mark XLVI)	Jean Grey (Phoenix)	Jeffrey (Symbiote)	Jessica Jones (Alias Investigations)
Jubilee (Phoenix Force)	Kamala Khan (Origin)	Kaine Parker (Scarlet Spider)	Kang (The Conqueror)
Killmonger (Erik Stevens)	Kingpin (Spider-Verse)	Kitty Pryde (Uncanny X-Men)	Knull (King in Black)
Loki (God of Mischief)	Magik (Phoenix Five)	Magneto (Age of Apocalypse)	May Parker (Spider-Girl)
Mephisto (Lord of Hell)	Miles Morales (Carnage Symbiote)	Mister Sinister (Nathaniel Essex)	Moon Knight (Avatar of Khonshu)
Namor (Phoenix Five)	Nova (Frankie Raye)	Nova (Tanak Valt)	Odin (All-Father)
Okoye (Warrior General)	Omega Red (Horseman of Pestilence)	Onslaught (Psionic Entity)	Peggy Carter (Worthy)
Phyla-Vell (Martyr)	Professor X (Classic)	Rescue (Pepper Potts)	Riri Williams (Ironheart 3.0)
Ronan (The Accuser)	Sam Wilson (Brave New World)	Scarlet Witch (WandaVision)	Sersi (Eternals)
Shang-Chi (Origin)	She-Hulk (Immortal)	Silver Surfer (Skyrider)	Spider-Gwen (Gwenom)
Spider-Man (Back In Black)	Spider-Man (Peter Parker)	Star-Lord (Awesome Mix Volume 2)	Storm (Ororo Munroe)
Thanos (The Mad Titan)	The Hulk (Bruce Banner)	The Hulk (Immortal)	The Hunter (Midnight Sun)
Thor (Gladiator)	Thor (Mighty Thor)	Toni Ho (Rescue)	Ultron (Age of Ultron)
Venomsaurus Rex (Brockiosaurus)	Victor Mancha (Victorious)	Vulture (Armor Wars)	Wasp (Hope Van Dyne)
Winter Soldier (Thunderbolts)	Wolverine (Old Man Logan)	Wolverine (Samurai Daken)	Wong (Sorcerer Supreme)
X-23 (Weapon Hex)	Yelena Belova (Black Widow)	Yellowjacket (Darren Cross)